Questions About Betammune:

What is Betammune, or Beta 1,3/1,6-D-Glucan?
Betammune is Beta 1,3/1,6-D-Glucan,
is a physician quality particulate polyglucose compound derived from the cell wall of baker’s yeast, or Saccharomyces Cerevisiae.  It is a purified natural-food based dietary supplement.  There are other sources of beta glucan, including mushrooms and oats.  However, these sources do not have the same activity level of the beta glucan that is derived from the cell wall of Saccharomyces Cerevisiae.  Scientific studies typically indicate that the best results for immune modulation are from beta glucan that has been derived from Saccharomyces Cerevisia.

How does Betammune or Beta-1/3,1/6-D-Glucan work?
Beta-1,3/1,6-D-Glucan has been implicated in the function of different physiological effects, from wound healing to immune potentiation.  Beta Glucan (Beta-1,3/1,6-D-Glucan) affects both the Innate and Adaptive Immune System, although it demonstrates greater affect on the Innate Immune System.  Within the Adaptive Immune System, it affects the T and B Lymphocytes and the specific biological mechanisms under their control.  Within the Innate Immune System, Beta Glucan serves as a very powerful immune stimulator by activating macrophage receptor sites.  Specific receptors articulate with the Beta Glucan polysaccharide chains cause the release of essential cytokines (IL-1, IL-6, GM-CSF, Interferons) evoking an immune response.  In addition, it enhances the following macrophage functions:  phagocytosis, production of wound growth factors, cellular adherence, chemostatic activity and cellular production and size.  Regarding the cell-mediated response within the Adaptive Immune System, Beta Glucan triggers T cells that orchestrate and regulate the general immune response.  It specifically orchestrates the potentiation of several cell lines among which are the CD3 and CD4 positive T cells which are responsible for alerting B cells.  It also affects CD8 positive T cells that have cytotoxic properties.  Therefore, it is evident that Beta Glucan serves to comprehensively potentiate the Immune System.

Is Beta Glucan backed by scientific research?
There is substantial documentation by leading researchers at prestigious institutions such as Harvard Medical School, Tulane University School of Medicine and McGill University regarding Beta Glucan.  Beta Glucan elicits broad anti-infective effects.  Protective benefits of Beta Glucan have been established against a wide range of microorganisms, including bacteria, fungi, viruses and parasites.  Staphylococcus aureus, Eschericia coli, Candida albicans, Pneumocytis carinii, Listeria monocytogenesis, Leishmania donovani, Herpes simplex and Ascaris suum, are just part of a list against which the protective benefits of Beta Glucan has been established.  Please also refer to our Research Page for copies of citations and abstracts.

Who should take Betammune?
BETAMMUNE should be considered for those individuals with impaired immune systems, acute and chronic health concerns, poor dietary habits, as well as those who are experiencing physical and/or emotional stress, those undergoing wound healing from surgery or injuries, and those who have been exposed to radiation and electromagnetic and ultraviolet exposure.  Additionally, protective benefits of Beta Glucan have been established against a wide range of microorganisms, including bacteria, fungi, viruses and parasites, as previously noted.

Additionally, over 1,000 studies have shown that high quality Beta Glucan is a potent macrophage activator that works synergistically with antibiotics, possesses powerful anti-fungal benefits, is effective against viral hepatitis, has been shown to have a direct anti-tumor effect, has protective benefits against radiotherapy, is an excellent wound healer, and possesses anti-oxidant properties.

What dosage of Betammune should be taken?
BETAMMUNE is supplied as 500mg. capsules in 60 count bottles.  Capsules should be taken 30 – 45 minutes before meals on an empty stomach.  Generally, a maintenance dosage is 500mg. to 1500mg. per day in divided doses.  However, the specific dosage recommendation will be determined by a number of factors, which should be determined by the healthcare practitioner based upon his or her professional clinical assessment and impression of his or her patient’s condition, constitution, individual needs, responses and other factors.  Upon request, we can supply to the practitioner a dosage recommendation guideline.  As always, the final decision regarding initial and subsequent dosage recommendations and implementation is the responsibility of the healthcare professional.*

What is the quality, or purity of Beta Glucan?
BETAMMUNE is a highly purified polyglucose compound extracted from the cell walls of baker’s yeast (Saccharomyces Cerevisiae) that is essentially protein free, non-allergenic and contains NO fillers or additives.  It has been shown to be non-toxic and without adverse side effects.  Additionally, Beta Glucan has been documented to provide great immune potentiating benefits.*

We certify that the percentage of Beta Glucan in Betammune is at least 77% as verified by an independent third party Certificate of Analysis.  We are confident that its quality and value will yield an effectiveness that will be unsurpassed.

Although some Beta Glucan products may contain a percentage greater than 77%, their additional cost and usually lesser milligrams per capsule provided does not offer any greater benefit.  Additionally, some Beta Glucan products may only contain either 100 mg. or 200 mg. per capsule, and may only contain 25% – 60% levels of purity.

Can Betammune be taken with other neutraceuticals or medications, and are there any side effects?
Beta Glucan is safe to take with other neutraceuticals or medications, and has been shown to enhance the effectiveness of antibiotics.

Because Betammune is highly purified, essentially protein free, and contains no fillers or additives, it has been shown to be non-toxic and without adverse side effects.

Can the immune system be over-stimulated by using Beta Glucan?
Betammune is an immune modulator, and by definition, does not over-stimulate the immune system.  As an immune modulator, its function is to modulate the immune system; that is, to adjust, regulate and keep the immune system in proper measure or proportion in concert with the organism as a whole.


Questions About Veramannan:

What is Veramannan, or Beta-1,4-Acetylated Glycomannan (AG)?
VERAMANNAN™  is Beta-1,4-Acetylated Glycomannan (AG) which is derived from the gel of the leaf of the Aloe Barbadensis Miller Plant.  The polysaccharide of Aloe is a long chain sugar molecule that is comprised of glucose and mannose sugar molecules connected together.  There is a large range in sizes of polysaccharide molecules.  The size and makeup of the molecule determines it’s effectiveness for various applications.  VERAMANNAN™ is composed predominantly of large polysaccharide long chain sugar molecules which measure in size from 500,000 – 2,000,000 Daltons.  Its primary healing action is that of an immune modulator.  Molecules in this size range have proven to have a powerful healing effect on conditions involving immune system dysfunction.

How does Veramannan, or Beta-1,4-Acetylated Glycomannan work?
The extra long polysaccharide chains in Beta-1,4-acetylated glycomannan have been implicated in the function of different physiological effects, from histamine reduction to immune potentiation. Acetylated Glycomannan (Beta-1,4) affects both the Innate and Adaptive Immune Systems, although it demonstrates greater affect on the Adaptive Immune System. Within the Innate Immune System, it affects the macrophage cells and the specific mechanisms under their control.  Beta-1,4-acetylated glycomannan activates the macrophage white blood cells through a specific receptor mediated pathway.  It stimulates macrophage activation by interacting with specialized receptors on the macrophage cell membrane, binding to four specific protein sites. Within the Adaptive Immune System, the following cell mediated immune functions are affected.  It affects the T and B Lymphocytes and the specific mechanisms under their control.  It specifically orchestrates the potentiation of several cell lines among which are the CD3 and CD4 positive T cells.  It also affects CD8 positive T cells with their cytotoxic properties. Therefore, it is evident that Acetylated Glycomannan serves to comprehensively potentiate the Immune System.

Is Beta-1,4-Acetylated Glycomannan backed by scientific research?
Numerous scientific studies have been performed by researchers who have substantiated the actions and effects of Beta-1,4-acetylated glycomannan.  Many scientific and clinical communities are aware of Beta-1,4-acetylated glycomannan’s efficaciousness.  Various scientific studies have yielded evidence of Beta-1,4-Acetylated Glycomannan’s effectiveness with regard to anti-tumor growth, anti-cancer properties, modulation of the immune system, phagocytosis stimulation, and stimulation of antibody formation.  Additionally, depressed phagocytic function of white blood cells may be increased in bronchial asthma patients, antiviral activity is exhibited and enhancement of cell function in some viral infections.  Of significant importance to note is that the polysaccharides bypass the digestive system intact and are absorbed by endocytosis (taken up into the cells of the intestinal lining intact and extruded into the circulatory system).  It is here that the immune supporting functions are fulfilled.

Who should take Veramannan?
VERAMANNAN™  should be strongly considered in those individuals who are undergoing physical stress, undergoing mental/emotional stress, have impaired immune systems, viral infections, bacterial infections, fungal infections, and those with advanced age.  Additionally, Veramannan may also potentially be beneficial for promoting immune system regulation, reducing histamine response, reducing allergies, promoting alleviation of bronchitis, aiding in the management of asthma, sinusitis management, increasing anti-viral protection, increasing anti-bacterial protection, increasing anti-fungal protection, reducing the reproduction of abnormal cells, reducing acute and chronic infections, addressing those with chronic fatigue syndrome and fibromyalgia, and aiding in the management of the common cold and flu, among others.

What dosage of Veramannan should be taken?
VERAMANNAN™ is supplied as 500mg. capsules in 60 count bottles, and should be taken 30-45 minutes before meals on an empty stomach.  In general, the recommended dosage is approximately 1500mg. per day for general maintenance in divided doses.  Like Betammune, dosages may vary depending upon the health status of the individual, and should be determined by the healthcare practitioner based upon his or her professional clinical assessment and impression of his or her patient’s condition, constitution, individual needs, responses and other factors.  Upon request, we can supply to the practitioner a dosage recommendation guideline.  As always, the final decision regarding initial and subsequent dosage recommendations and implementation is the responsibility of the healthcare professional.*

What is the quality, or purity of Beta-1,4-Acetylated Glycomannan?
The Aloe source utilized in our product is grown in rich soil since the fields sit on an old volcanic region.  Since harvesting is extremely important in the processing of Aloe, extreme care is taken to harvest at the correct time, utilizing the proper method.  Each leaf is carefully harvested by hand in a manner that insures that the leaf will “self-seal” to prevent oxidation and contamination.  Additionally, the leaves are processed the same day they are harvested, thereby retaining their freshness and minimizing bruising and other damage that could occur.

The powder concentrate in VERAMANNAN™  is derived from the Aloe Barbadensis Miller Plant and has been certified Organically Grown by Quality Assurance International.  The method used to extract the powder retains the greatest quality commensurate with the natural composition of the Aloe Barbadensis Miller Plant.  All other forms of processing which are used to derive Aloe Vera Plant products, denature the structure of the long chain polysaccharides, thereby rendering them ineffective as immune potentiators.  The VERAMANNAN™ product however, is unique in that it is derived by using a proprietary method of dehydration which preserves the long chain polysaccharides intact, yielding a powder concentrate of 200:1, primarily consisting of long polysaccharide chains endowed with immune potentiating activity.  The polysaccharide chains range in size from 140,000 to in excess of 2,000,000 Daltons.

Moreover, 70-79% of the extra long chain polysaccharides in the range of 500,000 – 2,000,000 Daltons are preserved and contained in this powder concentrate.  Our statement about this very high level of extra long chain polysaccharides has been verified by NMR studies.

Can Veramannan be taken with other neutraceuticals or medications, and are there any side effects?
Beta-1,4-Acetylated Glycomannan is safe to take with other neutraceuticals or medications, and is believed to have a synergistic effect when taken with Beta Glucan.

Because Veramannan is highly purified, essentially protein free, and contains no fillers or additives, it has been shown to be non-toxic and without adverse side effects.

Can the immune system be over-stimulated by using Beta-1,4-Acetylated Glycomannan?
Veramannan is an immune modulator, and by definition, does not over-stimulate the immune system.  As an immune modulator, its function is to modulate the immune system; that is, to adjust, regulate and keep the immune system in proper measure or proportion in concert with the organism as a whole.


Questions About MannanAloe:

What is MannanAloe, or Beta-1,4-Acetylated Glycomannan?
MANNANALOE  is Beta-1,4-Acetylated Glycomannan (AG) which is derived from the gel of the leaf of the Aloe Barbadensis Miller Plant.

The polysaccharide of this Aloe is a small, short chain sugar molecule that is comprised of glucose and mannose sugar molecules connected together.  There is a large range in sizes of polysaccharide molecules.  The size and makeup of the molecule determines it’s effectiveness for various applications.

MANNANALOE is composed predominantly of small polysaccharide short chain sugar molecules which measure in size from 10,000 – 100,000 Daltons.  Molecules in this size range have proven to have a powerful healing effect on inflammatory conditions, and have also been found to be effective in human studies in patients with Type II Diabetes and Insulin Resistance.

How does MannanAloe, or Beta-1,4-Acetylated Glycomannan work?
The short polysaccharide chains in Beta-1,4-acetylated glycomannan have been implicated in the function of different physiological effects.  Experiments have shown that total cholesterol levels were decreased, triglycerides levels were decreased, phospholipids levels were decreased, non-esterified fatty acid levels were decreased, HDL cholesterol levels were increased, and marked increase in the HDL/Total Cholesterol ratios was also noted.  The evidence suggests that the polysaccharide fraction of Aloe may reduce serum lipids.  Additional experiments have shown that it may also have a therapeutic effect on inflammatory bowel disease and ulcerative colitis, as well as an inhibitory effect on inflammation in conditions such as arthritis.

Is Beta-1,4-Acetylated Glycomannan (short chain) backed by scientific research?
Scientific studies have been performed by researchers who have substantiated the actions and effects of Beta-1,4-acetylated glycomannan.  Many scientific and clinical communities are aware of Beta-1,4-acetylated glycomannan’s efficaciousness.  It has been noted in various scientific studies which have yielded evidence that:  glycemic levels and triglyceride levels are normalized in patients with Type II Diabetes; glycemic levels and triglyceride levels are normalized in patients with Insulin Resistance; these molecules are potent anti-inflammatory agents that serve as anti-histamines, anti-bradykinins and other enzymes that are related to chronic inflammation such as arthritis; and, a therapeutic effect may be achieved with inflammatory bowel disease.

Who should take MannanAloe?
MANNANALOE should be strongly considered in those individuals with type II diabetes, with insulin resistance, with those undergoing allergic responses, with chronic inflammatory conditions, with bowel inflammatory conditions, with those that may have hyperpermeability syndrome (leaky gut), with arthritis and related conditions, and with ulcerative colitis and gastritis.

What dosage of MannanAloe should be taken?
MannanAloe is supplied as 500mg. capsules in 60 count bottles, and should be taken 30-45 minutes before meals on an empty stomach.  In general, the recommended dosage is approximately 1500mg. per day for general maintenance in divided doses.  Like Betammune and Veramannan, dosages may vary depending upon the health status of the individual, and should be determined by the healthcare practitioner based upon his or her professional clinical assessment and impression of his or her patient’s condition, constitution, individual needs, responses and other factors.  Upon request, we can supply to the practitioner a dosage recommendation guideline.  As always, the final decision regarding initial and subsequent dosage recommendations and implementation is the responsibility of the healthcare professional.*

What is the quality, or purity of Beta-1,4-Acetylated Glycomannan (short chain?
The Aloe source utilized in our product is grown in rich soil since the fields sit on an old volcanic region.  Since harvesting is extremely important in the processing of Aloe, extreme care is taken to harvest at the correct time, utilizing the proper method.  Each leaf is carefully harvested by hand in a manner that insures that the leaf will “self-seal” to prevent oxidation and contamination.  Additionally, the leaves are processed the same day they are harvested, thereby retaining their freshness and minimizing bruising and other damage that could occur.

The powder concentrate in MANNANALOE is derived from the Aloe Barbadensis Miller Plant and has been certified Organically Grown by Quality Assurance International.  The method used to extract the powder retains the greatest quality commensurate with the natural composition of the Aloe Barbadensis Miller Plant.  The MANNANALOE product however, is unique in that it is derived by using a proprietary method of dehydration yielding a powder concentrate of 200:1, primarily consisting of short polysaccharide chains that range in size from 12,000 to 150,000 Daltons.

Moreover, 98% of the short chain polysaccharides in the range of 12,000 – 150,000 Daltons are preserved and contained in this powder concentrate.  Our statement about these short chain polysaccharides has been verified by NMR studies.

Can MannanAloe be taken with other neutraceuticals or medications, and are there any side effects?
Beta-1,4-Acetylated Glycomannan (short chain) is safe to take with other neutraceuticals or medications, and is believed to have a synergistic effect when taken with Beta Glucan and Veramannan.

Because MannanAloe is highly purified, essentially protein free, and contains no fillers or additives, it has been shown to be non-toxic and without adverse side effects.

*The Statements contained within this document have not been evaluated by the Food and Drug Administration.  No statements made herein are intended, expressed and/or implied, to promote any product, or treat, prevent or cure any disease or condition.  The references should not be construed as express and/or implied representations, endorsements, guarantees and/or warranties of the company, and/or of any of the products that may be available from the company.  As a health care professional, please exercise your professional judgment in utilizing these, or any other products.   As always, the final decision regarding initial product recommendation, as well as the initial and subsequent dosage recommendations and implementation is the responsibility of the healthcare professional.

 

*Disclaimer:  The Statements contained within this document have not been evaluated by the Food and Drug Administration.  No statements made herein are intended, expressed and/or implied, to promote any product, or treat, prevent or cure any disease or condition. The references should not be construed as express and/ or implied representations, endorsements, guarantees and/or warranties of the company, and/or of any of the products that may be available from the company.  As a health care professional, please exercise your professional judgement in utilizing these, or any other products.  As always, the final decision regarding initial product recommendation, as well as the initial and subsequent dosage recommendations and implementation is the responsibility of the healthcare professional.